11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts inactive cortisone and
active cortisol. Although bidirectional, in vivo it is believed to function as a reductase …

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of disease ranging from
hepatocellular steatosis through steatohepatitis to fibrosis and irreversible cirrhosis. The …

Non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM) are common
conditions that regularly co-exist and can act synergistically to drive adverse outcomes. The …

I should like to thank the following people who have helped me in various ways in the writing
of this book: Martin Barker, Conrad Lodziak, Philip Schlesinger and Dave Woods. Many of …

… A lucid and engaging writer, John Tomlinson goes far beyond traditional discussions to
analyze the wide-ranging cultural, social, and moral aspects of globalization. Tomlinson begins …

Organic aerosol (OA) particles affect climate forcing and human health, but their sources and
evolution remain poorly characterized. We present a unifying model framework describing …

Lipoprotein(a) is an LDL-like lipoprotein whose concentration in plasma is correlated with
atherosclerosis. The characteristic protein component of lipoprotein(a) is apolipoprotein(a) …

Background Glucagon-like peptide-1 (GLP-1) analogues reduce hepatic steatosis, concentrations
of liver enzymes, and insulin resistance in murine models of fatty liver disease. These …

Purpose Resection of colorectal liver metastases (CLM) in selected patients has evolved as
the standard of care during the last 20 years. In the absence of prospective randomized …

… J Tomlinson analysed data and contributed to the writing of the paper; N Holden recruited
patients for and maintained the West Midlands hypopituitary database and was also involved …