We take for granted the ability to fall asleep or to snap out of sleep into wakefulness, but these
changes in behavioral state require specific switching mechanisms in the brain that allow …

… Both algorithms have been developed in large samples (n = 8000 for Horvath and n = 656
for Hannum) covering the entire adult life span and different ethnic populations. The Horvath …

… factors on the occurrence of angina pectoris and coronary heart disease (CHD) was
demonstrated in several early clinical studies in the registry summarized by deFaire and Pedersen […

Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic
architecture or its genetic relationship with other disorders. To discover loci associated …

We propose in this paper to use three regions of plastid DNA as a standard protocol for
barcoding all land plants. We review the other markers that have been proposed and discuss …

Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D),
we conducted a meta-analysis of genetic variants on the Metabochip, including …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

… We use the term N sum to indicate the total number of individuals when simply summing
them over the distinct cohorts. The script for the N eff computation is available online (see URLs)…

Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts
for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying …