User profiles for S. E. Holmes
Sophie E HolmesYale University Verified email at yale.edu Cited by 1589 |
Prevalence, clinical manifestations, etiology, and treatment of depression in Parkinson's disease
…, KA Slaughter, D Nichols, SE Holmes… - The Journal of …, 2001 - Am Neuropsych Assoc
… note that physical improvement in PD symptoms per se does not predict a concomitant
reduction in depression. It may be argued that although PD depression and PD disability from …
reduction in depression. It may be argued that although PD depression and PD disability from …
Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder
SE Holmes, JR Slaughter, J Kashani - Child psychiatry and human …, 2001 - Springer
… Recurrent CD symptoms may ensue with subsequent episodes of depression and anxiety,
but no study has determined that these episodes per se result in persistent antisocial …
but no study has determined that these episodes per se result in persistent antisocial …
Neurobiology of chronic stress-related psychiatric disorders: evidence from molecular imaging studies
Chronic stress accounts for billions of dollars of economic loss annually in the United States
alone, and is recognized as a major source of disability and mortality worldwide. Robust …
alone, and is recognized as a major source of disability and mortality worldwide. Robust …
[HTML][HTML] High frequency retrotransposition in cultured mammalian cells
We previously isolated two human L1 elements (L1.2 and LRE2) as the progenitors of
disease-producing insertions. Here, we show these elements can actively retrotranspose in …
disease-producing insertions. Here, we show these elements can actively retrotranspose in …
Expansion of a novel CAG trinucleotide repeat in the 5′ region of PPP2R2B is associated with SCA12
SE Holmes, EE O'Hearn, MG McInnis… - Nature …, 1999 - nature.com
The genetic aetiologies of at least 20% of autosomal dominant spinocerebellar ataxias (SCAs)
have yet to be elucidated 1. We have recently identified a novel form of autosomal …
have yet to be elucidated 1. We have recently identified a novel form of autosomal …
[HTML][HTML] Lower synaptic density is associated with depression severity and network alterations
SE Holmes, D Scheinost, SJ Finnema… - Nature …, 2019 - nature.com
Synaptic loss and deficits in functional connectivity are hypothesized to contribute to symptoms
associated with major depressive disorder (MDD) and post-traumatic stress disorder (…
associated with major depressive disorder (MDD) and post-traumatic stress disorder (…
A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease–like 2
SE Holmes, E O'Hearn, A Rosenblatt, C Callahan… - Nature …, 2001 - nature.com
We recently described a disorder termed Huntington disease–like 2 (HDL2) that completely
segregates with an unidentified CAG/CTG expansion in a large pedigree (W) 1. We now …
segregates with an unidentified CAG/CTG expansion in a large pedigree (W) 1. We now …
Elevated translocator protein in anterior cingulate in major depression and a role for inflammation in suicidal thinking: a positron emission tomography study
SE Holmes, R Hinz, S Conen, CJ Gregory… - Biological …, 2018 - Elsevier
Background Major depressive disorder is associated with raised peripheral inflammatory
markers. Mounting evidence also suggests that inflammation is involved in suicidal behavior. …
markers. Mounting evidence also suggests that inflammation is involved in suicidal behavior. …
Deconstructing differentiation: Self regulation, interdependent relating, and well-being in adulthood
EA Skowron, SE Holmes, RM Sabatelli - Contemporary family therapy, 2003 - Springer
This study examined underlying similarities between the Personal Authority in the Family
System Questionnaire (PAFS; Bray, Williamson, & Malone, 1984a) and the Differentiation of …
System Questionnaire (PAFS; Bray, Williamson, & Malone, 1984a) and the Differentiation of …
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion
SE Holmes, BA Dombroski, CM Krebs, CD Boehm… - Nature …, 1994 - nature.com
We have found a 2 kilobase insertion containing a rearranged L1 element in the dystrophin
gene of a muscular dystrophy patient. We cloned the precursor of this insertion, the second …
gene of a muscular dystrophy patient. We cloned the precursor of this insertion, the second …